Nucleic acid biosensor diagnostics. Inventors: U.J. Krull, P.A. Piunno, R.H. Hudson, A.H. Uddin, M.J. Damha; WO9858079; Nationalized in US 6,503,711; AU 755913; NZ 520303.
Antisense oligonucleotide constructs based on arabinose and its analogues. Inventors: M.J. Damha, M.A. Parniak, A. Noronha, C.J. Wilds, D. Arion, G. Borkow; WO 9967378 (priority date: 19-06-1998); Nationalized in CA 2,331,333; 2,241,361; EU 99 928945.7; US 09/19,870.
Chimeric antisense of arabinofuranose and deoxyribose nucleotides. Inventors: M.J. Damha, M.A. Parniak, C.-N. Lok, K. Viazovkina; Provisional application US 60/230,414 filed Sept. 6, 2000; WO 02020773; Nationalized in CA 2,419,563; SE 1969101.3; IT 1969101.3; NZ 0534396A; US 10/263,768, US 60/230,414; EU 01969191.3; AU 2001289448; JP 2002-525780.
Acyclic linker-containing oligonucleotides and uses thereof. Inventors: M.J. Damha, M.A. Parniak, M.M. Mangos, K.-L. Min, K. Viazovkina; Provisional application US 60/330,719 filed Oct. 29, 2001; WO 03037909; Nationalized in CA 2,465,129; DE 002060216798; NZ 532610; EP1440079B1; MX20004004056-A1; AU 2002/335,954; JP 2003-540190; US 10.494,141.
Oligonucleotides comprising alternating segments and uses thereof. Inventors: M.J. Damha, M.A. Parniak; Provisional application US 60/352,873 filed January 31, 2002; WO 03064441; Nationalized in CA 2,474,414; NZ 534,396; AU 2003/202376; EP 3700774.7; JP 2003-564061; MX PA/a/2004/00; US 10/503,120.
Compositions and methods for inhibiting RNase H activity of retroid reverse transcriptase. Inventors: M.J. Damha, R.N. Hannoush, K.-L. Min S. Carriero; Provisional application US 60/437,568 filed Dec. 12, 2002; US7501503 B2.
Ionic liquid supported synthesis. Inventors: T.-H. Chan, M.J. Damha, R.A. Donga, X. He, W. Miao; Provisional application US60/661,480 filed March 15, 2005; WO2006096963 A1; Nationalized in EP 06705308.2; JP 2008-501121; US 11/980,487; IN 3623/KOLNP/2007; CN 200680016812.9.
4'-Thioarabinonucleotide containing oligonucleotides, compounds and methods for their preparation and uses thereof. Inventors: M.J. Damha, J.K. Watts, B.M. Pinto; Provisional application US 60/750,838 filed Dec. 16, 2005; WO 2007068113.
2'-Deoxy-2'-fluoro-beta-D-arabinonucleoside 5'-triphosphates and their use in enzymatic nucleic acid synthesis. Inventors: M.J. Damha, C.G. Peng; Provisional application US 60/839,417 filed Aug. 23, 2006; WO 2008022469.
Oxepane nucleosides and oligonucleotides, uses thereof and methods of making the same. Inventors: M.J. Damha, D. Sabatino; Provisional application US60/841,203 filed Aug. 31, 2006; WO2008025160.
Oligonucleotide duplexes comprising DNA-like and RNA-like nucleotides and uses thereof. Inventors: M.J. Damha, J.K. Watts & Glen F. Deleavey; Provisional application US61/059,186 filed 05-06-2008; WO2009146556 A1.
Oligonucleotide Duplexes Comprising DNA-like and RNA-like Nucleotides and Uses Thereof. Inventors: Damha, M. J., Watts, J. K., Deleavey, G. F.; PCT/CA2009/000789 filed June 5, 2008;WO2009146556.
Immune Response Modulation and Uses Thereof. Inventors: Sonenberg, N., Costa-Mattioli, M., Colina Munoz, H. R., Svitkin, I. V., Alain, T., Damha, M. J., Deleavey, G. F.; PCT/CA2008/002259 filedDec. 19, 2007; WO2009076775.
RNA monomers containing O-acetal levulinyl ester groups and their use in RNA microarrays. Inventors: F. Cerrina, D. Mitra, M. Wickens, M.J. Damha, J.G. Lackey, A. Ansari; Provisional application US61/094,525 filed 9/8/2008; WO2010025566 A1.
Method for Reducing Expression of Downregulated in Renal Cell Carcinoma in Malignant Gliomas. Inventors: K. Petrecca, M.J. Damha, D.G. Deleavey; Provisional application US 20130197057 A1 filed May 18, 2010; CN103370414A, EP2571989A1, WO2011143762A1.